New Juaben South is the oldest of the thirty-three District Assemblies in the Eastern Region of Ghana. It covers an area of 60 Square Kilometers. It stretches between Latitude 60°70’W and Longitude 10°30’’ and 00°30’E. It shares boundaries on the North East with New Juaben North Municipal Assembly, West with Suhum Municipal, to the South-East with Akuapem North Municipal and Yilo Krobo Municipal to the East.

According to the 2010 Population and Housing Census report, Males Constitute 48.3 percent of the population and Female represents 51.7 percent. About 93.3 percent of the population live in urban localities. The municipality is predominantly urban. The municipality has a sex ratio of 100:93, implying that to every 100 females there are 93 males. The municipality has a youthful population of about 30.8 percent of the population below 15 years. This put enormous pressure on the Assembly to construct more schools and other social infrastructure to cater for their needs. Like all other developing countries, the age structure is broad at the base of the population pyramid and tapers off at the top. The total age dependency ratio for the municipally is 56.1 which implies that there are about 56 persons in the dependent age for every 100 persons in the working age group. The Municipality has a growth rate of 2.6 percent which is higher than the natural average of 2.1 percent.

As at 2018, the population of the Municipality was estimated at 222,459.